Correct me if I'm wrong, but RAM clocks don't make that big of a difference compared to the rest of your components (most places I've read about it say it's quite insignificant). He should be quite fine with the 1333mhz RAM, if he desires. Of course, if you want to overspend, be my guest.
My problem is that you haven't even considered monitors or SSDs and you're currently $521.80 away from your budget limit. To me this is a pathetic waste of 4k.
Good monitors (note: good, not that shit you see advertising itself as good for like 1xx dollars) run you a decent chunk. Even if you're telling me you're mostly using it for folding, when you DO want to game, you want to game on a GOOD monitor (or monitors, in your case). It makes quite a big difference. I'm running on a decent monitor that cost me 210 dollars, but this thing was refurbished, and at this price it was somewhat of a steal (2-3 dead pixels, too, not that it makes much of a difference). However, the difference was instantly noticeable. I'm looking at it side by side with my previous monitor, and the color differences are obvious.
I think a bit of rethinking on whether some of the more expensive components are necessary is in order. Processor, fine. You want to futureproof it. Motherboard... maybe look for slightly cheaper alternatives; the question is whether you'll need some of the things more expensive boards offer. I also don't see why you're getting such an expensive CPU cooler... but that's not that big of a price. Your graphics solution... fine. Now, the case... I must wonder if you can get something that's cheaper than that. Even for a computer of your caliber, something 100 dollars cheaper should suffice, imo. I'm not asking you to get a 50 dollar solution like I did (which works perfectly fine, by the way; I have 5 hard drives in it and everything is working harmoniously), but consider something more reasonable. Your first priority should be things that directly affect your computer performance; you can MAKE almost any case work.
