I'm very well aware that it's not a nice thing to say. But, if you can't have kids normally, don't. We have enough people walking around with inherent diseases as it is, no need to make more. I'm against it as I'm against IVF and the like.
If you wanted to get a career while you were in your 20's and only started thinking about family when you're in your 40's to 50's. Well, it sucks to be you, you traded away your chance for a career.
There's a reason why the chance of fertilization goes only downhill with every year once you have passed 21 or so, and with over 35's being in a "increased risk" zone. Guess what, 40 year old eggs do not make good healthy babies and as said earlier, it sucks to be you if you are in this position. But that is all it is, it just sucks to be you.