The problem I have with this show is, if they had the ability to manipulate the human genome to the extent that they did, why couldn't they just put
death feedback in normal humans too, instead of going through the trouble of turning them into queerats?
Also, near the end, he says
For the sake of peace, those with Cantus reprogrammed their DNA to include attack inhibition and death feedback
Why hasn't anyone (especially the super powerful dude with 4 pupils) tried un-doing these modifications that were made to their DNA?
Despite these oversights, the story was still magnificent and I managed to suspend my disbelief in spite of these plot holes.
I didn't mind the art, and the music was absolutely amazing.