it's like blaming Obama for what Bush did lol
lets end the silly arguing cuz there will be rage war soon about this, Tsunade sacrificed all of herself to help the village in the only way she could, by healing, if it wasn't for her and any other Hokage was there, Konoha wouldn't have much villagers left to rebuild it so I think your argument is invalid, lets say Sarutobi would go and fight, or Jiraiya if he was Hokage, they would die like anyone else, Naruto had a chance cuz he approached differently, he did defeat the 6 pains, but he did not defeat Nagato, he stopped him. Tsunade didn't make any mistake, Sasuke would have left anyways, be it Sarutobi or Jiraiya or anyone else, Orochimaru's henchmen came for him, and would have steal the boy anyways. Asuma died in combat, it wasn't Tsunade's fault, and Konoha would have been destroyed by Pain anyways, I mean, they didn't even know how to fight him in the first place, so if the Hokage would go fight him he would die like anyone else, Naruto was fully prepared for the fight, and he still barely made it.